The PREFI-CM consortium was born from the synergy relationship between clinicians, technicians and companies with a common interest in solving the risk of embolism in cardiac patients.

On the one hand, the cardiac imaging group of the HGUGM, led by Dr.Bermejo, provides a deep knowledge of cardiovascular disease, being a multidisciplinary group of physicists, engineers, technicians and cardiologists specialized in medical imaging. From a translational perspective, this group has been able to implement and patent innovative tools for the post-processing of signal and cardiovascular imaging which has resulted in novel physiological knowledge and diagnosis tools. The deep experience of this team in the application of physical and mathematical principles to cardiac imaging has already provided clinicians with robust non-invasive indices of function that are used in clinical practice.
On the other hand, the CFDLab research group of the Universidad Carlos III has a great experience in the generation of knowledge from the simulation of advanced fluid mechanics problems, including turbulence. Its incorporation into the study of intracavitary flow in the field of translational research is of paramount importance for the success of the consortium and the generation of applicable tools to clinical practice.

We believe that the interaction between these two approaches, technical and clinical will have an important effect in the study of the cardiac embolism and in its prevention

Steering Commitee

Javier Bermejo Thomas

Head of the Consortium/HGUGM group

Javier Bermejo joined the Department of Cardiology of the Hospital General Universitario Gregorio Marañón in Madrid, Spain as a fellow in 1992. Since then he has devoted his medical career to the field of patient care and cardiovascular imaging. He became Director of the Area of Noninvasive Cardiology and Cardiovascular Imaging in 2008, and he became Associate Professor in the Universidad Complutense de Madrid in 2019. His PhD thesis was dedicated to studying both to the invasive and noninvasive assessment of cardiac hemodynamics. Since then, he has been leading a technical, clinical and preclinical multidisciplinary research team integrated by clinical cardiologists, surgeons, engineers and physicists. He has received specific training in a number of fields of biomedical engineering, including advanced biostatistics, computer algorithm programming, image processing, and basic biomechanics. Dr. Bermejo research expertise is completely aligned with the PREFI-CM consortium, naturally following a long-standing research line dedicated to the characterization of novel aspects of cardiovascular hemodynamics from image postprocessing.

Manuel García-Villalba Navaridas

Head of the CFDLab group

Manuel García-Villalba did his Ph.D. in Engineering at the University of Karlsruhe (Germany) in 2006, where he worked in large eddy simulation of complex flows. Since 2016 he is an associate professor in the Aerospace Engineering section of the Universidad Carlos III de Madrid (Spain). He currently works on computational fluid dynamics with applications to aeronautical, mechanical and environmental engineering.

Pablo Martínez-Legazpi

Researcher at HGUGM

Pablo Martinez-Legazpi graduated in Mechanical Engineering in 2005 and finished his PhD thesis in Fluid Mechanics in 2011 in the University Carlos III of Madrid. In 2012 he moved to the University of California San Diego, serving as postdoctoral fellow for 2 years. He joined the Cardiology Department of the Hospital General Universitario Gregorio Marañón in 2014, aiming to apply fluid mechanics and engineering modeling to cardiovascular problems. He was awarded with the William W. Parmley Young Achievement Award by the ACC in 2015.

Oscar Flores

Head of the CFDLab group

Oscar Flores is an Aeronautical Engineer, with a PhD in Engineering from the Polytechnic University. He served as a research assistant at the Dep. Mechanical Engineering of the University of Washington (Seattle, USA) from 2008 to 2011. Then, he joined the Universidad Carlos III de Madrid (spain), becoming an associate professor in 2017. His research focuses on the study of the fundamental phenomena that appear in non-stationary and / or turbulent flows, using computational fluid mechanics and high performance computing tools.

Ana Fernández Baza


Ana Fernández Baza joined the department of Cardiology of the Hospital Gregorio Marañón in 2006 as a project manager. She has over fifteen years of experience managing national and international projects. She has participated in more than 50 organizers & technical committees of international meetings.