The Problem

Stroke is the second cause of death in developed countries, and 1/3 of them are caused by the formation of a thrombus inside the cardiac chambers. Intracardiac flow arrangement inside the heart plays an essential role in thrombosis. However, there is a lack of applied clinical tools allowing an appropriate characterization of flow phenomena inside the cardiac chambers.

Mision & Vision

We believe that an extensive analysis of intracardiac flow will provide more sensitive and specific information to predict the risk of cardiac embolism than current applied methods. This approach will help a personalized stratification and the clinical management of patients at risk of embolism, improving the decision-make process while prescribing anticoagulation therapy.


Real advances in clinical research will only be accomplished through collaboration. Thus, to guarantee the success of PREFICM, we have assembled a multidisciplinary team of experts in physics, engineering and cardiology of 5 different research institutions.


Our main goal points towards the generation new tools based on flow simulations from medical image to personalize anticoagulation in patients at risk of stroke.

Flow simulations from CT imaging.

We simulate flow inside the heart of each patient using CT scan images. The process is simple:

CT Medical image acquisition

A computed tomography (CT) scan of the heart is an imaging method that uses x-rays to create detailed pictures of the heart

Patient specific reconstruction of the heart

With the expertise of our team we are able to reassemble a 3D model of each patient’s heart

Flow simulation

Using the mesh obtained we can simulate the flow inside the heart

Stasis Mapping

From the flow field inside the heart we are able to predict were the blood may stagnant and activate clotting

Risk grading & Anticoagulation decision

Based on the stasis mapping results and the patient’s conditions, physicians may estimate the stroke risk.